BDBM559908 N-(3-{6-[(3R)-3-aminobut-1-yn-1-yl]-5- (morpholin-4-yl)pyridin-3-yl}-4- methylphenyl)-2- (trifluoromethyl)pyridine-4-carboxamide::US11377431, Example 20

SMILES C[C@@H](N)C#Cc1ncc(cc1N1CCOCC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=RAZNNQHFYBGEFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559908   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM559908(US11377431, Example 20 | N-(3-{6-[(3R)-3-aminobut-...)
Affinity DataIC50: 1nMAssay Description:Small molecule inhibition of the BRA and RAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test ...More data for this Ligand-Target Pair
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Date in BDB:
10/5/2022
Entry Details
US Patent