BDBM559953 4-(9-((4-chloro-1H-pyrazol-1-yl)methyl)-8,9-dihydro-7H-6-oxa-1,2,2a1-triazabenzo[cd]azulen-4-yl)-N-(1-methyl-1H-pyrazol-5-yl)pyridin-2-amine::US11376260, Example I-47R

SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OCC[C@H](Cn3cc(Cl)cn3)c3nnc(c1)n23

InChI Key InChIKey=JSSMLKORDMBRCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559953   

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM559953(US11376260, Example I-47R | 4-(9-((4-chloro-1H-pyr...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
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Date in BDB:
10/5/2022
Entry Details
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