BDBM560443 (2-((((2R,3S,4R,5R)-5-(6-chloro-4-((2- chlorobenzyl)amino)-1H-pyrazolo[3,4- d]pyrimidin-1-yl)-3,4- dihydroxytetrahydrofuran-2- yl)methyl)(methyl)amino)-2- oxoethyl)phosphonic acid::US11377469, Example 9

SMILES CN(C[C@@H]1CC[C@@H](O1)n1ncc2c(NCc3ccccc3Cl)nc(Cl)nc12)C(=O)CP(O)(O)=O

InChI Key InChIKey=CSOODJPXLUNKFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560443   

Target5'-nucleotidase(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM560443(US11377469, Example 9 | (2-((((2R,3S,4R,5R)-5-(6-c...)
Affinity DataIC50: 500nMAssay Description:Assay Reaction ConditionsAssay Volume: 70 μlReaction Volume: 50 μlCD73: 0.3208 nMAMP: 15 μMAssay Buffer: 2 5 mM Tris-HCL, pH 7.4, 0.01...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent