BDBM560697 (1R)-5-(3-Phenylazetidin-1-yl)-7-((tetrahydro-2H-pyran-4-yl)amino)-2,3-dihydrothieno[3,2-b]pyridine-1-oxide::US11384096, Example 7

SMILES [O-][S+]1CCc2nc(cc(NC3CCOCC3)c12)N1CC(C1)c1ccccc1

InChI Key InChIKey=LSHYNUZEOXGPKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560697   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandPNGBDBM560697(US11384096, Example 7 | (1R)-5-(3-Phenylazetidin-1...)
Affinity DataIC50: 30nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
US Patent