BDBM560871 5-((3'-methoxy-[1,1'- biphenyl]-4-yl)oxy)- 1H-1,2,3-triazole-4- carboxylic acid::US11389456, Ex. No. I-158

SMILES COc1cccc(c1)-c1ccc(Oc2cnn[nH]2)cc1

InChI Key InChIKey=QNIZRSIQGZWHEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560871   

Target2-Hydroxyacid oxidase 1(Human)
Oxalurx

US Patent
LigandPNGBDBM560871(US11389456, Ex. No. I-158 | 5-((3'-methoxy-[1,1'- ...)
Affinity DataIC50: 8nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

Target2-Hydroxyacid oxidase 1(Human)
Oxalurx

US Patent
LigandPNGBDBM560871(US11389456, Ex. No. I-158 | 5-((3'-methoxy-[1,1'- ...)
Affinity DataIC50: 5.00E+3nMAssay Description:A HepaRG human hepatic cell line was transfected for stable overexpression of the constitutive androstane receptor (i.e., HepaRG-CAR cells), as repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent