BDBM560878 5-([1,1'-biphenyl]-3- yloxy)-1H-1,2,3- triazole-4-carboxylic acid::US11389456, Ex. No. I-249

SMILES O(c1cnn[nH]1)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=VDMQQGRUMXNZLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560878   

Target2-Hydroxyacid oxidase 1(Human)
Oxalurx

US Patent
LigandPNGBDBM560878(US11389456, Ex. No. I-249 | 5-([1,1'-biphenyl]-3- ...)
Affinity DataIC50: 19nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

Target2-Hydroxyacid oxidase 1(Human)
Oxalurx

US Patent
LigandPNGBDBM560878(US11389456, Ex. No. I-249 | 5-([1,1'-biphenyl]-3- ...)
Affinity DataIC50: 2.00E+3nMAssay Description:A HepaRG human hepatic cell line was transfected for stable overexpression of the constitutive androstane receptor (i.e., HepaRG-CAR cells), as repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent