BDBM561055 (6-(4-((1H- indazol-5- yl)amino)- pyrimidin- 2-yl)-1H- indol-2-yl)(3.9- diazaspiro[5.5] undecan-3- yl)methanone::US11390609, Compound TDI01360

SMILES O=C(N1CCC2(CCNCC2)CC1)c1cc2ccc(cc2[nH]1)-c1nccc(Nc2ccc3[nH]ncc3c2)n1

InChI Key InChIKey=RRLLAUSRSZPDQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561055   

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561055((6-(4-((1H- indazol-5- yl)amino)- pyrimidin- 2-yl)...)
Affinity DataIC50: 26nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561055((6-(4-((1H- indazol-5- yl)amino)- pyrimidin- 2-yl)...)
Affinity DataIC50: 1.47E+3nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent