BDBM561111 6-(4-((4-(1H- pyrazol-4- yl)phenyl)- amino)- pyrimidin-2- yl)-N-(2,2,2- trifluoroethyl)- benzo[b]- thiophene-2- carboxamide::US11390609, Compound TDI01456

SMILES FC(F)(F)CNC(=O)c1cc2ccc(cc2s1)-c1nccc(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key InChIKey=YOJFRQRHCZDLTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561111   

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561111(6-(4-((4-(1H- pyrazol-4- yl)phenyl)- amino)- pyrim...)
Affinity DataIC50: 15nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561111(6-(4-((4-(1H- pyrazol-4- yl)phenyl)- amino)- pyrim...)
Affinity DataIC50: 1.00E+4nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent