BDBM561221 6-(4-((1H- indazol-5- yl)amino)- pyrimidin-2- yl)-N-(3- chloropyridin- 4-yl)-1-methyl- 1H-indole-2- carboxamide::US11390609, Compound TDI01841

SMILES Cn1c(cc2ccc(cc12)-c1nccc(Nc2ccc3[nH]ncc3c2)n1)C(=O)Nc1ccncc1Cl

InChI Key InChIKey=PYMFRFRTGCCYGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561221   

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561221(6-(4-((1H- indazol-5- yl)amino)- pyrimidin-2- yl)-...)
Affinity DataIC50: 11nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561221(6-(4-((1H- indazol-5- yl)amino)- pyrimidin-2- yl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent