BDBM561242 6-(4-((4-(1H- pyrazol-4- yl)phenyl)- amino)- pyrimidin-2- yl)-N-(3- morpholino- cyclohexyl)- 1H-indole-2- carboxamide::US11390609, Compound TDI01878

SMILES O=C(NC1CCCC(C1)N1CCOCC1)c1cc2ccc(cc2[nH]1)-c1nccc(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key InChIKey=IYHAVYVBJPACHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561242   

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561242(6-(4-((4-(1H- pyrazol-4- yl)phenyl)- amino)- pyrim...)
Affinity DataIC50: 9nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent