BDBM561254 (6-(4-((4-(1H- pyrazol-4- yl)phenyl)amino)-5- methoxypyrimidin- 2-yl)-1H-indol-2- yl)(3, 3- difluoroazetidin-1- yl)methanone::US11390609, Compound TDI01914

SMILES COc1cnc(nc1Nc1ccc(cc1)-c1cn[nH]c1)-c1ccc2cc([nH]c2c1)C(=O)N1CC(F)(F)C1

InChI Key InChIKey=BISUWZZRSXYLPT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561254   

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561254((6-(4-((4-(1H- pyrazol-4- yl)phenyl)amino)-5- meth...)
Affinity DataIC50: 23nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent