BDBM561726 US11390631, Example 263

SMILES C[C@H]1CN(CCO1)c1ncccc1-c1nnc(NC2N=C(c3ccccc3)c3ccccc3NC2=O)o1

InChI Key InChIKey=VNUAVBOJDFOHQT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 561726   

TargetMajor surface glycoprotein G()
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM561726(US11390631, Example 263 | US12268694, Example 263)
Affinity DataEC50:  600nMAssay Description:HEp-2 cells are seeded into the inner 60 wells of a 96-well plate at 8,000 cells per well in a volume of 50 μL using Growth Media (DMEM without pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetMajor surface glycoprotein G()
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM561726(US11390631, Example 263 | US12268694, Example 263)
Affinity DataEC50:  600nMAssay Description:A549 cells (originally derived through explant culture from a 58 year old male's carcinomatous lung tissue) are seeded into the inner 60 wells of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetGag-Pol polyprotein(ALV-A RSA)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM561726(US11390631, Example 263 | US12268694, Example 263)
Affinity DataEC50:  600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

TargetGag-Pol polyprotein(ALV-A RSA)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM561726(US11390631, Example 263 | US12268694, Example 263)
Affinity DataEC50:  600nMAssay Description:The description is Japanese.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent