BDBM562166 6-(Indoline-1-carbonyl)-3,4-dihydro-1H-1,8-naphthyridin-2-one::US11401256, Example 58

SMILES O=C(N1CCc2ccccc12)c1cnc2NC(=O)CCc2c1

InChI Key InChIKey=WOOBFBFFSBDDCE-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562166   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM562166(US11401256, Example 58 | 6-(Indoline-1-carbonyl)-3...)
Affinity DataKd:  62nMAssay Description:Process 1) Optimization of measurement parameters to minimize protein consumption and to minimize the dilution effect and the DMSO content 2) Titrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
US Patent