BDBM562407 US11401279, Example 1

SMILES Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

InChI Key InChIKey=CRUAYBHDGFNLAV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562407   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Human)
Incyte

US Patent

LigandBDBM562407(US11401279, Example 1)Copy SMILESCopy InChI

Affinity DataIC50: 2.20nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/23/2022
Entry Details
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