BDBM562419 US11401279, Example 12

SMILES C[C@@H]1C[C@H](O)CN1Cc1cnc2c(Nc3cccc(c3C)-c3cccc(NC(=O)c4nc5CN(CCC67CCC(CC6)(C7)C(O)=O)CCc5n4C)c3Cl)nc(nc2c1)C(F)F

InChI Key InChIKey=GMHZYPMISVQEAR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562419   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Human)
Incyte

US Patent

LigandBDBM562419(US11401279, Example 12)Copy SMILESCopy InChI

Affinity DataIC50: 1.5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/23/2022
Entry Details
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