BDBM562610 US11406645, Compound 503

SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCC(C)(C)O)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=CYUUSRGILFWDHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562610   

TargetBromodomain testis-specific protein [22-138](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM562610(US11406645, Compound 503)
Affinity DataIC50: 89nMAssay Description:Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-167](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM562610(US11406645, Compound 503)
Affinity DataIC50: 44nMAssay Description:Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent