BDBM562900 4-[2-methyl-5-[(3S)-3-(2,2,2- trifluoroethyl)pyrrolidine-1- carbonylamino]phenyl]-6-(morpholin-4- yl)pyridine-2-carboxamide::US11407737, Example 2

SMILES Cc1ccc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)cc1-c1cc(nc(c1)C(N)=O)N1CCOCC1

InChI Key InChIKey=PFZBOHAMIPSWHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562900   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM562900(US11407737, Example 2 | 4-[2-methyl-5-[(3S)-3-(2,2...)
Affinity DataIC50: 5.5nMAssay Description:Assay platform was used to measure kinase/inhibitor interactions as described previously (Anastassiadis et al., 2011). In brief, for each reaction, k...More data for this Ligand-Target Pair
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Date in BDB:
10/28/2022
Entry Details
US Patent