BDBM563080 (3S)-N-[4-methyl-3-[2-(l-methylpyrazol- 4-yl)-6-(morpholin-4-yl)pyridin-4- yl]phenyl]-3-(2,2,2- trifluoroelhyl)pyrrolidine-1-carboxamide::US11407737, Example 22

SMILES Cc1ccc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)cc1-c1cc(nc(c1)-c1cnn(C)c1)N1CCOCC1

InChI Key InChIKey=DUANSMMAXOYRKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563080   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM563080(US11407737, Example 22 | (3S)-N-[4-methyl-3-[2-(l-...)
Affinity DataIC50: 1nMAssay Description:Assay platform was used to measure kinase/inhibitor interactions as described previously (Anastassiadis et al., 2011). In brief, for each reaction, k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent