BDBM563081 (2R)-N-{4-methyl-3-[2-(2- methylpyrazol-3-yl)-6-(morpholin-4- yl)pyridin-4-yl]phenyl}-2- (trifluoromethyl)morpholine-4- carboxamide::US11407737, Example 65

SMILES Cc1ccc(NC(=O)N2CCO[C@H](C2)C(F)(F)F)cc1-c1cc(nc(c1)-c1ccnn1C)N1CCOCC1

InChI Key InChIKey=GUBHOQAZCBUXTN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563081   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM563081(US11407737, Example 65 | (2R)-N-{4-methyl-3-[2-(2-...)
Affinity DataIC50: 1nMAssay Description:Assay platform was used to measure kinase/inhibitor interactions as described previously (Anastassiadis et al., 2011). In brief, for each reaction, k...More data for this Ligand-Target Pair
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Date in BDB:
10/28/2022
Entry Details
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