BDBM563091 (3S)-N-{2-fluoro-4-methyl-5-[2-methyl 6-(morpholin-4-yl)pyridin-4-yl]phenyl} 3-(2,2,2-trifluoroethyl)pyrrolidine-1- carboxamide::US11407737, Example 70

SMILES Cc1cc(cc(n1)N1CCOCC1)-c1cc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)c(F)cc1C

InChI Key InChIKey=XGYIOJFNFJRYHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563091   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM563091(US11407737, Example 70 | (3S)-N-{2-fluoro-4-methyl...)
Affinity DataIC50: 1nMAssay Description:Assay platform was used to measure kinase/inhibitor interactions as described previously (Anastassiadis et al., 2011). In brief, for each reaction, k...More data for this Ligand-Target Pair
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Date in BDB:
10/28/2022
Entry Details
US Patent