BDBM563176 (2S,4R)-N-(6- bromopyridin-2- yl)-4-fluoro-1-(2- (3-((E)-1- (hydroxyimino)eth- yl)-5-(2- methylpyrimidin-5- yl)-1H-indazol-1- yl)acetyl)pyrrolidine- 2-carboxamide::US11407738, Example 00351

SMILES C\C(=N/O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(cc12)-c1cnc(C)nc1

InChI Key InChIKey=JWDHNPPHXYNBGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563176   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM563176(US11407738, Example 00351 | (2S,4R)-N-(6- bromopyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent