BDBM563200 ((1S,3S,5R)-2-(2- (3-acetyl-5-(2- methylpyrimidin-5- yl)-1H-indazol-1- yl)acetyl)-3-((6- bromopyridin-2- yl)carbamoyl)-2- azabicyclo[3.1.0]hex- an-5-yl)methyl diethyl phosphate::US11407738, Example 00375::US11407738, Example 00417

SMILES CCOP(=O)(OCC)OC[C@@]12C[C@@H]1N([C@@H](C2)C(=O)Nc1cccc(Br)n1)C(=O)Cn1nc(C(C)=O)c2cc(ccc12)-c1cnc(C)nc1

InChI Key InChIKey=AJSNKKKHCUFVIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563200   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM563200(US11407738, Example 00375 | ((1S,3S,5R)-2-(2- (3-a...)
Affinity DataIC50: 5.50E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM563200(US11407738, Example 00375 | ((1S,3S,5R)-2-(2- (3-a...)
Affinity DataIC50: 5.50E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent