BDBM563256 6-(3-(((S)-1-fluoropropan-2-yl)amino)-2-(4-((4-((3-methoxyazetidin-1-yl)methyl)phenyl)ethynyl)phenyl)propyl)-5-hydroxypyrimidin-4(3H)-one ::US11407740, Compound 68

SMILES COC1CN(Cc2ccc(cc2)C#Cc2ccc(cc2)C(CN[C@@H](C)CF)Cc2nc[nH]c(=O)c2O)C1

InChI Key InChIKey=BYIWDLCODFFARC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563256   

TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli (strain K12))
Forge Therapeutics

US Patent
LigandPNGBDBM563256(US11407740, Compound 68 | 6-(3-(((S)-1-fluoropropa...)
Affinity DataIC50: 30nMAssay Description:IC50 values against E. coli LpxC were determined using a Rapid Fire MS assay as previously described J. Med. Chem. 2012, 55, 1662-1670.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent