BDBM563337 US11407754, Example 11

SMILES CCn1cc(Nc2nc(N(C)[C@@H]3CC[C@H](C)N(C3)C(=O)C=C)c3c(Cl)n[nH]c3n2)cn1

InChI Key InChIKey=IJHNBFBDGXMGDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563337   

TargetTyrosine-protein kinase BTK(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM563337(US11407754, Example 11)
Affinity DataIC50: 0.900nMAssay Description:JAK3 and BTK kinases inhibitory activities were measured for the compounds prepared in the Examples through in vitro analysis on the ADP Glow (Glo) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM563337(US11407754, Example 11)
Affinity DataIC50: 5.70nMAssay Description:JAK3 and BTK kinases inhibitory activities were measured for the compounds prepared in the Examples through in vitro analysis on the ADP Glow (Glo) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent