BDBM563341 N-(4-(4-methoxy-2- ((4-((4- methylpiperidin-1- yl)methyl)phenyl)amino)- 7H-pyrrolo[2,3- d]pyrimidin-5- yl)phenyl)methane- sulfonamide::US11407757, Cpd 4

SMILES COc1nc(Nc2ccc(CN3CCC(C)CC3)cc2)nc2[nH]cc(-c3ccc(NS(C)(=O)=O)cc3)c12

InChI Key InChIKey=ATJORKOQGVNLQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 563341   

TargetTyrosine-protein kinase receptor UFO(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563341(US11407757, Cpd 4 | N-(4-(4-methoxy-2- ((4-((4- me...)
Affinity DataIC50: 30nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Axl kinase. Inhibition of Axl kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563341(US11407757, Cpd 4 | N-(4-(4-methoxy-2- ((4-((4- me...)
Affinity DataIC50: 65nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Mer kinase. Inhibition of Mer kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563341(US11407757, Cpd 4 | N-(4-(4-methoxy-2- ((4-((4- me...)
Affinity DataIC50: 700nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Met kinase. Inhibition of Met kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent