BDBM563365 4-(4-methoxy-2-((4- ((4-methylpiperidin-1- yl) methyl)phenyl)amino)- 7H-pyrrolo[2,3-d] pyrimidin-5-yl)phenol::US11407757, Cpd 28

SMILES COc1nc(Nc2ccc(CN3CCC(C)CC3)cc2)nc2[nH]cc(-c3ccc(O)cc3)c12

InChI Key InChIKey=ACRSYDLSAYZZOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 563365   

TargetTyrosine-protein kinase receptor UFO(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563365(US11407757, Cpd 28 | 4-(4-methoxy-2-((4- ((4-methy...)
Affinity DataIC50: 30nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Axl kinase. Inhibition of Axl kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563365(US11407757, Cpd 28 | 4-(4-methoxy-2-((4- ((4-methy...)
Affinity DataIC50: 65nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Mer kinase. Inhibition of Mer kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563365(US11407757, Cpd 28 | 4-(4-methoxy-2-((4- ((4-methy...)
Affinity DataIC50: 250nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Met kinase. Inhibition of Met kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent