BDBM563367 5-(2,4- difluorophenyl)-4- methoxy- N-(4-((4-methyl piperidin-1-yl) methyl)phenyl)-7H- pyrrolo[2,3- d]pyrimidin-2-amine::US11407757, Cpd 30

SMILES COc1nc(Nc2ccc(CN3CCC(C)CC3)cc2)nc2[nH]cc(-c3ccc(F)cc3F)c12

InChI Key InChIKey=USOBXZYMQTZFQG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 563367   

TargetTyrosine-protein kinase receptor UFO(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563367(US11407757, Cpd 30 | 5-(2,4- difluorophenyl)-4- me...)
Affinity DataIC50: 30nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Axl kinase. Inhibition of Axl kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563367(US11407757, Cpd 30 | 5-(2,4- difluorophenyl)-4- me...)
Affinity DataIC50: 65nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Mer kinase. Inhibition of Mer kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563367(US11407757, Cpd 30 | 5-(2,4- difluorophenyl)-4- me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Met kinase. Inhibition of Met kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent