BDBM563404 5-(2-methyl benzo[d]oxazol-6-yl)- N-(4-((4-methyl piperazin-1-yl)methyl) phenyl)-4- ((tetrahydrofuran-2-yl) methoxy)-7H-pyrrolo [2,3-d]pyrimidin-2- amine::US11407757, Cpd 67

SMILES CN1CCN(Cc2ccc(Nc3nc(OCC4CCCO4)c4c(c[nH]c4n3)-c3ccc4nc(C)oc4c3)cc2)CC1

InChI Key InChIKey=UNJQFDLOVSTMRV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 563404   

TargetTyrosine-protein kinase receptor UFO(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563404(US11407757, Cpd 67 | 5-(2-methyl benzo[d]oxazol-6-...)
Affinity DataIC50: 30nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Axl kinase. Inhibition of Axl kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563404(US11407757, Cpd 67 | 5-(2-methyl benzo[d]oxazol-6-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Mer kinase. Inhibition of Mer kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM563404(US11407757, Cpd 67 | 5-(2-methyl benzo[d]oxazol-6-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Certain compounds of formula (I) were tested for their potency in inhibiting Met kinase. Inhibition of Met kinase activity by a test compound was cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent