BDBM563489 (S)-2-amino-3-(4-(2- amino-7-((3'-methoxy- [1,1'-biphenyl]-4- yl)methyl)-7H- pyrrolo[2,3- d]pyrimidine-4- yl)phenyl)propionic acid hydrochloride::US11407763, Example 12

SMILES COc1cccc(c1)-c1ccc(Cn2ccc3c(nc(N)nc23)-c2ccc(C[C@H](N)C(O)=O)cc2)cc1

InChI Key InChIKey=PWFKELXSDGUJQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563489   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563489((S)-2-amino-3-(4-(2- amino-7-((3'-methoxy- [1,1'...)
Affinity DataIC50: 297nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent