BDBM563490 US11407763, Example 22::ethyl (S)-2-amino-3-(4- (4-((R)-1-(4-chloro-2- (3-methyl-1H-pyrazole- 1-yl)phenyl)-2,2,2- trifluoroethoxy)thieno [3,2-d]pyrimidine-7- yl)phenyl)propionate hydrochloride

SMILES CCOC(=O)[C@@H](N)Cc1ccc(cc1)-c1csc2c(O[C@H](c3ccc(Cl)cc3-n3ccc(C)n3)C(F)(F)F)ncnc12

InChI Key InChIKey=XLGRGWHHVBWRRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563490   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563490(ethyl (S)-2-amino-3-(4- (4-((R)-1-(4-chloro-2- (...)
Affinity DataIC50: 993nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
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Date in BDB:
11/5/2022
Entry Details
US Patent