BDBM563620 Tetrahydro-pyran-4-carboxylic acid [4-(2-{2-[3-(5-tert-butyl-2-p- tolyl-2H-1-pyrazol-3-yl)-ureido]- thiazol-5-yl}-ethyl)-pyridin-2-yl]- amide::US11407771, Compound 288

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ncc(CCc2ccnc(NC(=O)C3CCOCC3)c2)s1)C(C)(C)C

InChI Key InChIKey=NUEOPKXFUKVPLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563620   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563620(US11407771, Compound 288 | Tetrahydro-pyran-4-carb...)
Affinity DataIC50: 114nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563620(US11407771, Compound 288 | Tetrahydro-pyran-4-carb...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent