BDBM563629 US11407771, Compound 262::[4-(4-{3-[5-(3-Methyl-thietan-3- yl)-2-p-tolyl-2H-pyrazol-3-yl]- ureido}-phenoxy)-pyridin-2-yl]- carbamic acid methyl ester

SMILES COC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C3(C)CSC3)cc2)ccn1

InChI Key InChIKey=GXRMCPKKTHASHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563629   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563629(US11407771, Compound 262 | [4-(4-{3-[5-(3-Methyl-t...)
Affinity DataIC50: 37nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563629(US11407771, Compound 262 | [4-(4-{3-[5-(3-Methyl-t...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent