BDBM563630 1-[4-(2-Amino-pyridin-4-yloxy)- 2-fluoro-phenyl]-3-[5-tert-butyl- 2-(3-fluoro-phenyl)-2H-pyrazol- 3-yl]-urea::US11407771, Compound 304

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(N)c3)cc2F)n(n1)-c1cccc(F)c1

InChI Key InChIKey=KWZBHFNADSMZHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563630   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563630(US11407771, Compound 304 | 1-[4-(2-Amino-pyridin-4...)
Affinity DataIC50: 36nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563630(US11407771, Compound 304 | 1-[4-(2-Amino-pyridin-4...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent