BDBM563636 N-{4-[2-(2-{3-[5-tert-Butyl-2-(3- fluoro-phenyl)-2H-pyrazol-3-yl]- ureido}-thiazol-5-yl)-ethyl]- pyridin-2-yl}-acetamide::US11407771, Compound 320

SMILES CC(=O)Nc1cc(CCc2cnc(NC(=O)Nc3cc(nn3-c3cccc(F)c3)C(C)(C)C)s2)ccn1

InChI Key InChIKey=AJZDUXBUXXPGPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563636   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563636(US11407771, Compound 320 | N-{4-[2-(2-{3-[5-tert-B...)
Affinity DataIC50: 18nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563636(US11407771, Compound 320 | N-{4-[2-(2-{3-[5-tert-B...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent