BDBM563638 2-Methoxy-N-[4-(4-{3-[5-(3- methyl-oxetan-3-yl)-2-p-tolyl-2H- pyrazol-3-yl]-ureido}-phenoxy)- pyridin-2-yl]-acetamide::US11407771, Compound 259

SMILES COCC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C3(C)COC3)cc2)ccn1

InChI Key InChIKey=XIXPUHSPHAHNFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563638   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563638(US11407771, Compound 259 | 2-Methoxy-N-[4-(4-{3-[5...)
Affinity DataIC50: 15nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563638(US11407771, Compound 259 | 2-Methoxy-N-[4-(4-{3-[5...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent