BDBM563639 N-(4-{4-[3-(5-tert-Butyl-2- isopropyl-2H-pyrazol-3-yl)- ureido]-3-fluoro-phenoxy}- pyridin-2-yl)-acetamide::US11407771, Compound 392

SMILES CC(C)n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(NC(C)=O)c2)cc1F)C(C)(C)C

InChI Key InChIKey=AOMMXQCXSIAZQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563639   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563639(US11407771, Compound 392 | N-(4-{4-[3-(5-tert-Buty...)
Affinity DataIC50: 12nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563639(US11407771, Compound 392 | N-(4-{4-[3-(5-tert-Buty...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent