BDBM563646 1-(5-tert-Butyl-2- cyclopropylmethyl-2H-pyrazol- yl)-3-[2-fluoro-4-(pyridin-4- yloxy)-phenyl]-urea::US11407771, Compound 310

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccncc3)cc2F)n(CC2CC2)n1

InChI Key InChIKey=YUVYIYAJYYHGJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563646   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563646(US11407771, Compound 310 | 1-(5-tert-Butyl-2- cycl...)
Affinity DataIC50: 6nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563646(US11407771, Compound 310 | 1-(5-tert-Butyl-2- cycl...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent