BDBM563666 N-(4-{3-fluoro-4-[3-(2-fluoro- trimethylsilanyl-phenyl)-ureido]- phenoxymethyl}-pyridin-2-yl)- acetamide::US11407771, Compound 405

SMILES CC(=O)Nc1cc(COc2ccc(NC(=O)Nc3cc(ccc3F)[Si](C)(C)C)c(F)c2)ccn1

InChI Key InChIKey=HPJPRJAIKCAAID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563666   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563666(US11407771, Compound 405 | N-(4-{3-fluoro-4-[3-(2-...)
Affinity DataIC50: 51nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563666(US11407771, Compound 405 | N-(4-{3-fluoro-4-[3-(2-...)
Affinity DataIC50: 625nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent