BDBM563685 1-[4-(2-Amino-pyridin-4-yloxy)- 2-fluoro-phenyl]-3-(5-tert-butyl- 2-chloro-phenyl)-urea::US11407771, Compound 428

SMILES CC(C)(C)c1ccc(Cl)c(NC(=O)Nc2ccc(Oc3ccnc(N)c3)cc2F)c1

InChI Key InChIKey=QWLQGDDKNWXDBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563685   

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563685(US11407771, Compound 428 | 1-[4-(2-Amino-pyridin-4...)
Affinity DataIC50: 95nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563685(US11407771, Compound 428 | 1-[4-(2-Amino-pyridin-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent