BDBM563700 Roche-Dataset for PDE10A, Compound 14

SMILES Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccn2nc(nc2c1)-c1ccccc1OCCF

InChI Key InChIKey=QUEDGAVIKVSJNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563700   

LigandPNGBDBM563700(Roche-Dataset for PDE10A, Compound 14)
Affinity DataIC50: 0.350nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details Article
PubMed