BDBM5650 3-(5-Chlorothien-3-yl)-5-(carbamoylamino)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 24j::[3-(5-chlorothiophen-3-yl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]urea

SMILES NC(=O)Nc1cccc2-c3n[nH]c(-c4csc(Cl)c4)c3C(=O)c12

InChI Key InChIKey=AGIIDJZSMZSLJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5650   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5650(3-(5-Chlorothien-3-yl)-5-(carbamoylamino)indeno[1,...)
Affinity DataIC50: 13nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5650(3-(5-Chlorothien-3-yl)-5-(carbamoylamino)indeno[1,...)
Affinity DataIC50: 57nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed