BDBM565092 (R)-N-(1-cyanopyrrolidin- 3-yl)-[1,1'-biphenyl]-4- sulfonamide::US11414402, Example 3

SMILES O=S(=O)(N[C@@H]1CCN(C1)C#N)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=CWHZUYIHGGINNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 565092   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM565092(US11414402, Example 3 | (R)-N-(1-cyanopyrrolidin- ...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM565092(US11414402, Example 3 | (R)-N-(1-cyanopyrrolidin- ...)
Affinity DataIC50: 5.50E+4nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent