BDBM565142 US11414404, Ex. # 19::US11634409, Example 19

SMILES Cc1c(Nc2c(F)cnc(NS(=O)(=O)CCCF)c2Cl)ccc2ncn(C)c(=O)c12

InChI Key InChIKey=GUAHFOFVZPLLJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 565142   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandPNGBDBM565142(US11414404, Ex. # 19 | US11634409, Example 19)
Affinity DataIC50: 6.20nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
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Date in BDB:
10/30/2022
Entry Details
US Patent