BDBM565217 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(methylsulfonyl)azetidin-3-yl) acetamide::US11414413, Example 14

SMILES CS(=O)(=O)N1CC(CC(N)=O)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12

InChI Key InChIKey=SEOZWZLGYKHYMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 565217   

TargetTyrosine-protein kinase JAK2(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM565217(US11414413, Example 14 | 2-(3-(4-(7H-pyrrolo[2,3-d...)
Affinity DataIC50: 35nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM565217(US11414413, Example 14 | 2-(3-(4-(7H-pyrrolo[2,3-d...)
Affinity DataIC50: 35nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM565217(US11414413, Example 14 | 2-(3-(4-(7H-pyrrolo[2,3-d...)
Affinity DataIC50: 50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent