BDBM566463 US11419874, Lu AF64280

SMILES CN1CCN(CC1)c1ccc(Oc2nn3c(nnc3c3ccccc23)-c2ccccc2Cl)cc1

InChI Key InChIKey=XQMWTFPJNNPXAG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 566463   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Oslo University Hospital

US Patent
LigandPNGBDBM566463(US11419874, Lu AF64280)
Affinity DataKi:  20nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Oslo University Hospital

US Patent
LigandPNGBDBM566463(US11419874, Lu AF64280)
Affinity DataKi:  1.80E+3nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent