BDBM566473 ((S)-3-cyclopropyl-6- methyl-1-(1-(4- (trifluoromethoxy) phenyl)propan-2-yl)- 1,5-dihydro-4H- pyrazolo[3,4-d] pyrimidin-4-one::US11419874, PDM-631

SMILES C[C@@H](Cc1ccc(OC(F)(F)F)cc1)n1nc(C2CC2)c2c1nc(C)[nH]c2=O

InChI Key InChIKey=VHMPTEZWTNAXPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 566473   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Oslo University Hospital

US Patent
LigandPNGBDBM566473(US11419874, PDM-631 | ((S)-3-cyclopropyl-6- methyl...)
Affinity DataIC50: 1.5nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Oslo University Hospital

US Patent
LigandPNGBDBM566473(US11419874, PDM-631 | ((S)-3-cyclopropyl-6- methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent