BDBM566483 N-(cyanomethyl)-5-(4- (trifluoromethyl)phenoxy)-2- naphthamid::US11420935, Compound 22

SMILES FC(F)(F)c1ccc(Oc2cccc3cc(ccc23)C(=O)NCC#N)cc1

InChI Key InChIKey=BWIBNEYCDPQBGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 566483   

TargetLuciferin 4-monooxygenase(Southern Russian firefly)
Vivace Therapeutics

US Patent
LigandPNGBDBM566483(N-(cyanomethyl)-5-(4- (trifluoromethyl)phenoxy)-2-...)
Affinity DataIC50: 100nMAssay Description:The Dual-Glo Luciferase Reagent was prepared by transferring the contents of one bottle of Dual-Glo Luciferase Buffer to one bottle of Dual-Glo Lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM566483(N-(cyanomethyl)-5-(4- (trifluoromethyl)phenoxy)-2-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of YAP in HEK293T cells incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed