BDBM567850 US11420970, Example 51::US11420970, Example 54

SMILES Nc1ncnc2n(Cc3cc(ncc3N3CCC[C@](N)(Cc4ccccn4)C3)-c3ccc(F)c(F)c3)cnc12

InChI Key InChIKey=PIAMYQASYPHGPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 567850   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Novartis

US Patent
LigandPNGBDBM567850(US11420970, Example 54 | US11420970, Example 51)
Affinity DataIC50: 5.5nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase NSD2(Human)
Novartis

US Patent
LigandPNGBDBM567850(US11420970, Example 54 | US11420970, Example 51)
Affinity DataIC50: 5.5nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent