BDBM567915 US11420970, Example 116

SMILES Nc1ncnc2n(Cc3cc(ncc3N3CCC[C@@](N)(C3)[C@H](O)C(F)F)-c3ccc(OC(F)F)c(F)c3)cnc12

InChI Key InChIKey=MWTXNOKOEWEHGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 567915   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Novartis

US Patent
LigandPNGBDBM567915(US11420970, Example 116)
Affinity DataIC50: 5.5nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent