BDBM568538 (R)-(3-aminopiperidin-1-yl)(2-(1-((3-fluoropyridin-2-yl)methyl)-1H-indol-2-yl)-3-methylimidazo[1,2-a]pyridin-7-yl)methanone::US11426412, Compound 62

SMILES Cc1c(nc2cc(ccn12)C(=O)N1CCC[C@@H](N)C1)-c1cc2ccccc2n1Cc1ncccc1F

InChI Key InChIKey=QNNSIOLCWAIXJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 568538   

TargetProtein-arginine deiminase type-4(Human)
Jubilant Epipad

US Patent
LigandPNGBDBM568538((R)-(3-aminopiperidin-1-yl)(2-(1-((3-fluoropyridin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Citrullination assay was detected via ammonia release. PAD4 was diluted to 120 nM in assay buffer (100 mM HEPES, 50 mM NaCl, 2 mM DDT, 0.6 mg/mL BSA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent